Description

4-Amino-2-Fluoro-5-Nitrobenzonitrile is a high-purity, multi-functional aromatic nitrile building block of significant interest in advanced organic synthesis. Its unique structure, featuring amino, fluoro, and nitro substituents, makes it a versatile intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science sectors for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for targeted therapies and fluorinated drug candidates.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and pesticides, where the fluorine atom can enhance biological activity and stability.
• Material Science Research: Serves as a building block for advanced polymers, liquid crystals, and organic electronic materials due to its electron-withdrawing nitro and nitrile groups.
• Dye and Pigment Intermediate: Employed in the synthesis of specialized dyes and pigments where the amino and nitro groups are crucial for color development.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D in organic chemistry, enabling the exploration of new reaction pathways and heterocyclic systems.

Basic Information

Product Name	4-Amino-2-Fluoro-5-Nitrobenzonitrile
CAS No.	143151-03-5
Molecular Formula	C7H4FN3O2
Molecular Weight	181.12 g/mol
Synonyms	2-Fluoro-4-amino-5-nitrobenzonitrile; 5-Nitro-2-fluoro-4-aminobenzonitrile; Benzonitrile, 4-amino-2-fluoro-5-nitro-; 4-Amino-2-fluoro-5-nitrobenzenecarbonitrile; 143151-03-5; 2-Fluoro-4-cyano-5-nitroaniline; 4-Cyano-2-fluoro-5-nitroaniline
EINECS	Contact for details

Quality Control

Our 4-Amino-2-Fluoro-5-Nitrobenzonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.