Description

2'-Decarboxy-2'-Aminostreptonigrin is a structurally modified derivative of the potent antitumor antibiotic, streptonigrin. This compound is of significant interest in pharmaceutical research and development due to its potential as a key intermediate or active scaffold for novel therapeutic agents. It is primarily utilized by research institutions and pharmaceutical companies engaged in oncology drug discovery, chemical biology studies, and the synthesis of complex natural product analogs.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel anticancer drug candidates and targeted therapies.
• Oncology Research: Used as a reference standard or probe compound in biochemical assays to study mechanisms of cell death and DNA interaction.
• Chemical Biology: Employed in structure-activity relationship (SAR) studies to optimize the potency and selectivity of streptonigrin-derived molecules.
• Academic Research: Utilized in university and institutional labs for fundamental research on quinone-based antibiotics and their modes of action.
• Preclinical Development: Acts as a starting material for the preparation of analogs intended for in vitro and in vivo efficacy and toxicity testing.

Basic Information

Product Name	2'-Decarboxy-2'-Aminostreptonigrin
CAS No.	143139-76-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	2'-Amino-2'-decarboxystreptonigrin; 2'-Decarboxy-2'-aminostreptonigrin; Aminodecarboxystreptonigrin; Streptonigrin derivative, 2'-amino-2'-decarboxy-; 2'-Amino-2'-deoxycarbonylstreptonigrin
EINECS	Contact for details

Quality Control

Our 2'-Decarboxy-2'-Aminostreptonigrin is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research applications. A Certificate of Analysis (COA) detailing batch-specific results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term storage, consider keeping the material under inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	Brown to dark brown powder
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Water Content	≤ 5.0%
Residue on Ignition	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.