Description

Phosphetane, 1,1-Bis(1,1-Dimethylethyl)-1-Fluoro-1,1-Dihydro- CAS NO 142160-11-0 is a highly specialized organophosphorus compound featuring a unique fluorinated phosphacyclobutane (phosphetane) ring structure. This compound is valued for its role as a key intermediate and ligand precursor in advanced chemical synthesis, particularly in the development of novel catalysts and materials. It is primarily utilized by pharmaceutical R&D teams, academic research laboratories, and specialty chemical manufacturers focused on organometallic chemistry and fluorine chemistry.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel drug candidates, especially those incorporating phosphorus or fluorine for enhanced bioactivity.
• Catalyst Ligand Precursor: Used to synthesize sophisticated phosphine-based ligands for transition metal catalysis in fine chemical and polymer production.
• Organometallic Research: A valuable reagent in academic and industrial research for studying new reaction pathways and stabilizing reactive metal centers.
• Material Science: Investigated for the development of advanced polymeric materials, flame retardants, and electronic chemicals where phosphorus-fluorine bonds impart specific properties.
• Agrochemical Synthesis: Potential intermediate in the research and development of next-generation pesticides and herbicides.
• Fluorine Chemistry Studies: Employed as a model compound to explore the reactivity and stability of fluorinated organophosphorus species.

Basic Information

Product Name	Phosphetane, 1,1-Bis(1,1-Dimethylethyl)-1-Fluoro-1,1-Dihydro-
CAS No.	142160-11-0
Molecular Formula	C11H22FP
Molecular Weight	204.27 g/mol
Synonyms	1-Fluoro-1,1-di-tert-butylphosphetane; 1,1-Di-tert-butyl-1-fluorophosphetane; 1-Fluoro-1,1-bis(tert-butyl)phosphetane; tert-Butylfluorophosphetane; Fluorodi-tert-butylphosphetane; 1-Fluoro-1,1-bis(1,1-dimethylethyl)phosphetane; 1,1-Di-tert-butylfluorophosphetane; 1-Fluoro-1,1-di-t-butylphosphetane
EINECS	Contact for details

Quality Control

Our production of Phosphetane, 1,1-Bis(1,1-Dimethylethyl)-1-Fluoro-1,1-Dihydro- adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including NMR, GC, and HPLC analysis, to ensure high chemical purity and structural integrity. We provide detailed Certificates of Analysis (COA) with every shipment, documenting key parameters such as assay, identity, and impurity profiles. Our quality systems are designed to support research and cGMP-grade applications where traceability and consistency are paramount.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This compound is sensitive to moisture and strong bases; ensure the container is kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Purity (GC)	≥ 95.0%
Purity (HPLC)	≥ 94.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.