Description

[11Beta,16Alpha(S)]-16,17-[(Cyclohexylmethylene)Bis(Oxy)]-11-Hydroxy-21-(2-Methyl-1-Oxopropoxy)-Pregna-1,4-Diene-3,20-Dione is a high-purity synthetic steroid derivative with a complex, multi-functional molecular structure. This compound is of significant value in advanced pharmaceutical research and development, particularly as a key intermediate or active pharmaceutical ingredient (API) for novel therapeutic agents. It is primarily needed by research institutions, pharmaceutical manufacturers, and fine chemical suppliers engaged in the development of steroidal drugs targeting inflammation, immune response, and other endocrine-related pathways.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the multi-step synthesis of novel corticosteroid or other steroidal active pharmaceutical ingredients (APIs).
• Research & Development: Used in preclinical and clinical research to study structure-activity relationships (SAR) and develop new anti-inflammatory or immunosuppressive therapies.
• Reference Standard: Employed as a high-purity analytical standard for quality control and method validation in pharmaceutical laboratories.
• Process Chemistry: Utilized in scale-up and optimization studies for the commercial manufacturing of complex steroid-based drugs.
• Biochemical Research: Applied in studies investigating steroid hormone receptor binding and modulation.

Basic Information

Product Name	[11Beta,16Alpha(S)]-16,17-[(Cyclohexylmethylene)Bis(Oxy)]-11-Hydroxy-21-(2-Methyl-1-Oxopropoxy)-Pregna-1,4-Diene-3,20-Dione
CAS No.	141845-81-0
Molecular Formula	C₃₄H₄₈O₇
Molecular Weight	568.75 g/mol
Synonyms	21-Isovaleryloxy-11β,16α,17α-trihydroxypregna-1,4-diene-3,20-dione 16,17-Cyclohexylidene ketal; 11β,16α,17α,21-Tetrahydroxypregna-1,4-diene-3,20-dione cyclic 16,17-acetal with cyclohexanone 21-isovalerate; (11β,16α)-16,17-[(Cyclohexylmethylene)bis(oxy)]-11,21-dihydroxypregna-1,4-diene-3,20-dione 21-(2-methylpropanoate); Steroid Cyclohexylidene Ketal Derivative; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our [11Beta,16Alpha(S)]-16,17-[(Cyclohexylmethylene)Bis(Oxy)]-11-Hydroxy-21-(2-Methyl-1-Oxopropoxy)-Pregna-1,4-Diene-3,20-Dione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets exacting pharmaceutical-grade standards. Comprehensive Certificates of Analysis (COA) detailing all test results are provided to guarantee traceability, consistency, and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a dry environment and protected from light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.