Description

Mometasone Furoate Hydrate CAS NO 141646-00-6 is a synthetic corticosteroid ester, widely recognized for its potent anti-inflammatory and anti-pruritic properties. This high-purity active pharmaceutical ingredient (API) is critical for the development of safe and effective topical and intranasal pharmaceutical formulations. It is an essential raw material for pharmaceutical manufacturers and R&D institutions focused on dermatology, allergy, and respiratory therapeutics.

Application

• Topical Corticosteroid Creams and Ointments: Primary API for treating inflammatory skin conditions such as eczema, psoriasis, and dermatitis.
• Nasal Sprays: Key ingredient in formulations for the management of allergic rhinitis and nasal polyps.
• Pharmaceutical Research & Development (R&D): Used as a reference standard and for developing new drug delivery systems and generic medications.
• Veterinary Pharmaceuticals: Employed in topical preparations for treating inflammatory skin disorders in animals.
• Analytical Testing: Serves as a high-purity standard for quality control and assay development in analytical laboratories.

Basic Information

Product Name	Mometasone Furoate Hydrate
CAS No.	141646-00-6
Molecular Formula	C₂₇H₃₀Cl₂O₆ • xH₂O
Molecular Weight	521.43 (Anhydrous basis)
Synonyms	Mometasone Furoate Monohydrate; 9,21-Dichloro-11β,17-dihydroxy-16α-methylpregna-1,4-diene-3,20-dione 17-(2-furoate); Sch 32088; USAN; Elocon; Nasonex; Mometasone 17-(2-Furoate) Hydrate; 11β,17,21-Trihydroxy-16α-methylpregna-1,4-diene-3,20-dione cyclic 17,21-acetal with acetone 21-(2-furoate)
EINECS	Contact for details

Quality Control

Our Mometasone Furoate Hydrate is manufactured under strict quality systems. Each batch is tested to ensure it meets stringent specifications for identity, purity, and potency, aligning with pharmacopeial standards. A comprehensive Certificate of Analysis (COA) documenting results for assay, related substances, residual solvents, and other critical parameters is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to standard
Identification (HPLC)	Conforms to standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	3.0% - 6.0%
Related Substances (HPLC)	Individual impurity: NMT 0.5% Total impurities: NMT 2.0%
Residual Solvents (GC)	Complies with ICH Q3C
Heavy Metals	NMT 20 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.