Description

9-Oxo Epinastine Hydrochloride is a key pharmaceutical intermediate and a derivative of the antihistamine Epinastine. This compound is critical for researchers and manufacturers developing new therapeutic agents, particularly in the field of allergy and inflammation. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical synthesis facilities for the production and analysis of advanced active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of Epinastine and its related analogs for medicinal chemistry research.
• Reference Standard: Used as a high-purity analytical standard in quality control (QC) and research & development (R&D) laboratories for method development and validation.
• Active Pharmaceutical Ingredient (API) Research: Serves as a precursor in the development and scale-up of new pharmaceutical formulations targeting histamine H1-receptor antagonism.
• Biochemical Research: Employed in pharmacological studies to investigate the structure-activity relationships (SAR) of antihistamine compounds.
• Process Chemistry: Used in the optimization of synthetic routes for the commercial manufacturing of related therapeutic agents.

Basic Information

Product Name	9-Oxo Epinastine Hydrochloride
CAS No.	141342-69-0
Molecular Formula	C16H15N3O•HCl
Molecular Weight	293.77 g/mol
Synonyms	9-Oxoepinastine Hydrochloride; 3-Amino-9,13b-dihydro-1H-dibenz[c,f]imidazo[1,5-a]azepin-9-one Hydrochloride; Epinastine Impurity; Epinastine Related Compound; 9-Keto Epinastine HCl; 9-Oxo-Epinastine HCl; (3-Amino-9,13b-dihydro-1H-dibenz[c,f]imidazo[1,5-a]azepin-9-one) hydrochloride
EINECS	Contact for details

Quality Control

Our 9-Oxo Epinastine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the stringent requirements for pharmaceutical research and development. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.