Description

7-o-(2,6-Dideoxy-2-Fluoro-4-o-(3-Fluorotetrahydropyran-2-Yl)Talopyrano Syl)Daunomycinone CAS NO 141291-21-6 is a chemically modified anthracycline derivative, representing a sophisticated intermediate in advanced pharmaceutical synthesis. This compound is of critical importance for research and development in novel oncology therapeutics, offering a pathway to more potent and targeted anti-cancer agents. It is primarily needed by pharmaceutical R&D laboratories, biotechnology firms, and academic institutions focused on developing next-generation chemotherapeutics and studying structure-activity relationships in anthracycline antibiotics.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel, fluorinated daunorubicin or doxorubicin analogs for cancer treatment research.
• Oncology Drug Discovery: Used in medicinal chemistry programs to develop new anthracycline-based chemotherapeutic agents with potentially improved efficacy or reduced cardiotoxicity.
• Biochemical Research: Serves as a precise molecular tool for studying the mechanism of action of topoisomerase II inhibitors and DNA intercalation.
• Structure-Activity Relationship (SAR) Studies: Essential for investigating how specific fluorination and sugar moiety modifications affect the biological activity and pharmacokinetics of anthracycline drugs.
• Reference Standard: Can be utilized as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Preclinical Development: Supports the early-stage development and scale-up processes for experimental anti-cancer compounds.

Basic Information

Product Name	7-o-(2,6-Dideoxy-2-Fluoro-4-o-(3-Fluorotetrahydropyran-2-Yl)Talopyrano Syl)Daunomycinone
CAS No.	141291-21-6
Molecular Formula	C32H35F2NO11
Molecular Weight	647.62 g/mol
Synonyms	7-O-(2,6-Dideoxy-2-fluoro-4-O-(3-fluorotetrahydropyran-2-yl)-α-L-talopyranosyl)daunomycinone; Daunomycinone, 7-O-(2,6-dideoxy-2-fluoro-4-O-(3-fluorotetrahydropyran-2-yl)-α-L-talopyranosyl)-; Fluorinated Daunorubicin Derivative; 7-O-(2,6-Dideoxy-2-fluoro-4-O-(3-fluorotetrahydropyran-2-yl)-α-L-talopyranosyl)-13-dihydrodaunomycinone; 141291-21-6; Talopyranosyl Daunomycinone Fluorinated Analog; 4'-Fluoro-3'-fluorotetrahydropyranyl Daunomycinone Glycoside
EINECS	Contact for details

Quality Control

Our 7-o-(2,6-Dideoxy-2-Fluoro-4-o-(3-Fluorotetrahydropyran-2-Yl)Talopyrano Syl)Daunomycinone is manufactured under strict quality systems suitable for research and pharmaceutical intermediate applications. Each batch undergoes rigorous analytical testing including HPLC for purity, NMR and MS for structural confirmation, and determination of residual solvents to ensure compliance with internal specifications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurities is provided with every shipment to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant and inert atmosphere.

Specification

Item	Specification
Appearance	Yellow to orange-red powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (NMR)	Spectrum consistent with structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.