Description

2-Fluoro-6-Hydroxybenzonitrile is a versatile fluorinated aromatic nitrile building block with a reactive phenolic hydroxyl group. This compound is valued for its role as a key intermediate in the synthesis of complex molecules, particularly in advanced pharmaceutical and agrochemical research. It is essential for chemists and manufacturers in the life sciences and specialty chemical sectors seeking to introduce fluorine and specific substitution patterns into their target compounds.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for molecules requiring a fluorinated aromatic core.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides where the fluorine atom enhances biological activity and stability.
• Liquid Crystal Materials: Serves as a building block for fluorinated liquid crystal compounds used in display technologies.
• Organic Synthesis Building Block: Utilized in coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and for constructing complex heterocycles in medicinal chemistry.
• Polymer Chemistry: Can be incorporated as a monomer or modifier to create specialty polymers with unique thermal or chemical resistance properties.
• Research & Development: A valuable reagent for academic and industrial R&D exploring new fluorinated chemical entities.

Basic Information

Product Name	2-Fluoro-6-Hydroxybenzonitrile
CAS No.	140675-43-0
Molecular Formula	C7H4FNO
Molecular Weight	137.11 g/mol
Synonyms	2-Fluoro-6-hydroxybenzonitrile; 6-Cyano-3-fluorophenol; 2-Cyano-3-fluorophenol; 3-Fluoro-2-hydroxybenzonitrile; 2-Hydroxy-6-fluorobenzonitrile; Benzonitrile, 2-fluoro-6-hydroxy-; 140675-43-0; 2-Fluoro-6-hydroxy-benzonitrile
EINECS	Contact for details

Quality Control

Our 2-Fluoro-6-Hydroxybenzonitrile is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by FT-IR and NMR spectroscopy, to ensure it meets the high standards required for synthetic applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents, strong bases, and strong acids.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.