Description

4'-(Trifluoromethyl)[1,1'-Biphenyl]-4-Carbonitrile is a high-purity, multi-functional biphenyl derivative featuring a trifluoromethyl group and a nitrile moiety. This compound is a critical advanced pharmaceutical intermediate and a versatile building block for the synthesis of complex organic molecules. It is primarily utilized by research and development teams in the pharmaceutical, agrochemical, and material science industries to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the development of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Serves as a core structure for creating novel herbicides, fungicides, and insecticides, leveraging the stability imparted by the trifluoromethyl group.
• Liquid Crystal & OLED Materials: Used in the research and production of advanced electronic display materials due to its rigid biphenyl core and electron-withdrawing groups.
• Organic Light-Emitting Diodes (OLEDs): Acts as an electron-transport material or a host material in emissive layers.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to construct more complex conjugated systems.
• Chemical Research & Development: A valuable reference standard and building block in academic and industrial R&D for exploring new synthetic pathways.

Basic Information

Product Name	4'-(Trifluoromethyl)[1,1'-Biphenyl]-4-Carbonitrile
CAS No.	140483-60-9
Molecular Formula	C14H8F3N
Molecular Weight	247.22 g/mol
Synonyms	[4-(Trifluoromethyl)phenyl]benzonitrile; 4'-(Trifluoromethyl)biphenyl-4-carbonitrile; 4-Cyano-4'-(trifluoromethyl)biphenyl; p-Cyanophenyl(trifluoromethyl)benzene; 1,1'-Biphenyl-4-carbonitrile, 4'-(trifluoromethyl)-; 4-(4-Cyanophenyl)benzotrifluoride; 4-Trifluoromethyl-4'-cyanobiphenyl
EINECS	Contact for details

Quality Control

Our 4'-(Trifluoromethyl)[1,1'-Biphenyl]-4-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment ensures the material is suitable for demanding applications in GMP-intermediate synthesis and advanced research.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flames. The container should be kept tightly sealed to prevent contamination and moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.