Description

3,5-Difluorobenzenesulfonamide is a high-purity fluorinated aromatic sulfonamide building block of significant interest in advanced organic synthesis. Its core value lies in its dual functionality, serving as a versatile precursor for constructing complex molecules in pharmaceutical and agrochemical research. This compound is primarily needed by R&D chemists and process development scientists in the life sciences sector for applications such as medicinal chemistry, where it acts as a key intermediate for sulfonamide-based bioactive compounds.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly those targeting enzymes where the sulfonamide moiety is a key pharmacophore.
• Agrochemical Synthesis: Used in the development of new herbicides and fungicides, leveraging the biological activity of fluorinated sulfonamides.
• Material Science Research: Serves as a monomer or functionalizing agent in the creation of specialized polymers and advanced materials with unique properties.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes and inhibitors for studying biological pathways and protein function.
• Custom Synthesis & Contract Manufacturing: A starting material for custom synthesis services catering to the specific needs of biotechnology and fine chemical companies.

Basic Information

Product Name	3,5-Difluorobenzenesulfonamide
CAS No.	140480-89-3
Molecular Formula	C6H5F2NO2S
Molecular Weight	193.17 g/mol
Synonyms	Benzenesulfonamide, 3,5-difluoro-; 3,5-Difluorobenzene-1-sulfonamide; 3,5-Difluorophenylsulfonamide; 1-Sulfamoyl-3,5-difluorobenzene; 3,5-Difluoro-benzenesulfonic acid amide; NSC 405124; AI3-52011
EINECS	Contact for details

Quality Control

Our 3,5-Difluorobenzenesulfonamide is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to meet the exacting standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	142 - 146 °C
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.