Description

2-[(4-Fluorophenyl)Amino]Isonicotinonitrile is a specialized heterocyclic organic compound featuring a pyridine core substituted with a nitrile group and a 4-fluoroanilino moiety. This molecular architecture makes it a valuable key intermediate in the synthesis of more complex pharmacologically active molecules. It is primarily utilized by pharmaceutical R&D and fine chemical synthesis teams engaged in developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Research: Used in the development of new active ingredients for crop protection products, leveraging its fluorinated aromatic structure.
• Material Science: Acts as a precursor for the synthesis of specialized ligands and functional monomers used in advanced polymeric materials.
• Chemical Synthesis: Employed in academic and industrial research for constructing complex heterocyclic frameworks via its reactive cyano and amino groups.
• Bioconjugation Probe Development: Its structure can be modified to create probes for studying biological interactions and enzyme activity.

Basic Information

Product Name	2-[(4-Fluorophenyl)Amino]Isonicotinonitrile
CAS No.	137225-11-7
Molecular Formula	C12H8FN3
Molecular Weight	213.21 g/mol
Synonyms	2-[(4-Fluorophenyl)amino]pyridine-4-carbonitrile; 4-Cyano-2-[(4-fluorophenyl)amino]pyridine; 2-Amino-4-cyano-4'-fluorodiphenylamine; Isonicotinonitrile, 2-[(4-fluorophenyl)amino]-; 4-Pyridinecarbonitrile, 2-[(4-fluorophenyl)amino]-
EINECS	Contact for details

Quality Control

Our production of 2-[(4-Fluorophenyl)Amino]Isonicotinonitrile adheres to strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are available upon request, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.