Description

2,3,6-Trifluorobenzonitrile CAS NO 136514-17-5 is a high-purity fluorinated aromatic nitrile building block essential for advanced organic synthesis. Its unique substitution pattern makes it a critical intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by R&D and process development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of fluorine-containing drugs where the trifluoromethyl or difluoromethyl groups are introduced.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, leveraging the stability and lipophilicity imparted by the fluorine atoms.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated liquid crystal compounds and electron-transport materials in organic light-emitting diodes (OLEDs).
• Polymer Modification: Acts as a monomer or modifier to incorporate fluorine into polymer backbones, enhancing chemical resistance, thermal stability, and lowering surface energy.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to create biaryl structures common in many functional materials.
• Fluorinated Dye & Pigment Synthesis: Employed in the manufacture of specialized fluorinated dyes and pigments that offer improved lightfastness and unique chromatic properties.

Basic Information

Product Name	2,3,6-Trifluorobenzonitrile
CAS No.	136514-17-5
Molecular Formula	C7H2F3N
Molecular Weight	157.09 g/mol
Synonyms	2,3,6-Trifluorobenzonitrile; Benzonitrile, 2,3,6-trifluoro-; 2,3,6-Trifluorophenyl cyanide; 2,3,6-Trifluorobenzene carbonitrile; 136514-17-5; 2,3,6-Trifluoro-benzonitrile; 2,3,6-Trifluorobenzonitrile (GC grade)
EINECS	Contact for details

Quality Control

Our 2,3,6-Trifluorobenzonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical characteristics is provided with every shipment to guarantee consistent quality and traceability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Purity (GC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.