Description

Diphenyl(2,2,2-Trifluoroethyl)Sulfanium Trifluoromethanesulfonate is a specialized organosulfur salt, widely recognized as a powerful and versatile reagent in advanced organic synthesis. Its core value lies in its ability to act as an efficient trifluoromethylation and sulfonium-based alkylating agent, enabling the introduction of valuable fluorinated groups into complex molecular architectures. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors, where precise fluorination is critical for modulating the biological activity, stability, and physical properties of target molecules.

Application

• Pharmaceutical Intermediate Synthesis: Key reagent for the late-stage trifluoromethylation of drug candidates to enhance metabolic stability and bioavailability.
• Agrochemical Development: Used in creating novel pesticides and herbicides with improved efficacy and environmental profile through selective fluorination.
• Advanced Material Production: Facilitates the synthesis of fluorinated monomers and polymers for specialty coatings, electronics, and high-performance resins.
• Organic Methodology Research: A pivotal tool in academic and industrial R&D for developing new C-C and C-S bond-forming reactions under mild conditions.
• Ligand and Catalyst Preparation: Employed in the synthesis of sophisticated ligands and organocatalysts containing sulfonium or trifluoromethyl motifs.
• Radiochemistry and Tracer Synthesis: Useful for incorporating fluorine-19 or as a precursor analog for positron emission tomography (PET) tracer development.

Basic Information

Product Name	Diphenyl(2,2,2-Trifluoroethyl)Sulfanium Trifluoromethanesulfonate
CAS No.	135654-49-8
Molecular Formula	C16H14F6O3S2
Molecular Weight	432.40 g/mol
Synonyms	Diphenyl(2,2,2-trifluoroethyl)sulfonium trifluoromethanesulfonate; (2,2,2-Trifluoroethyl)diphenylsulfonium Triflate; Trifluoroethyl Diphenyl Sulfonium Triflate; S-(2,2,2-Trifluoroethyl)diphenylsulfonium Trifluoromethanesulfonate; Diphenyl(trifluoroethyl)sulfonium Triflate; 135654-49-8; Sulfonium, diphenyl(2,2,2-trifluoroethyl)-, trifluoromethanesulfonate (1:1)
EINECS	Contact for details

Quality Control

Our production of Diphenyl(2,2,2-Trifluoroethyl)Sulfanium Trifluoromethanesulfonate adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. All materials undergo rigorous analytical testing, including NMR, HPLC, and elemental analysis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality management and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when opening to prevent degradation. Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.