Description

Maduropeptin B is a specialized bioactive compound belonging to the enediyne class of antitumor antibiotics, identified by CAS number 134910-72-8. This compound is of significant interest in pharmaceutical research due to its potent DNA-cleaving activity, which is a critical mechanism for developing novel chemotherapeutic agents. It serves as a key reference standard and research material for scientists in oncology, biochemistry, and medicinal chemistry, enabling the study of enediyne mechanisms and the development of new cancer therapies.

Application

• Pharmaceutical Research & Development: As a reference standard for the study of enediyne antitumor antibiotics and their mechanism of action.
• Oncology Drug Discovery: Used in biochemical assays to investigate DNA damage and apoptosis pathways for potential new cancer treatments.
• Academic Research: A critical tool in university and institutional labs for studying microbial natural products and their bioactivity.
• Biochemical Reagent: Employed in enzymatic and cell-based studies to understand cellular responses to DNA strand breaks.
• Analytical Standard: Used in HPLC, LC-MS, and NMR for method development, validation, and quality control of related compounds.

Basic Information

Product Name	Maduropeptin B
CAS No.	134910-72-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Maduropeptin B; Maduropeptin B (Antibiotic); 134910-72-8; Enediyne antibiotic Maduropeptin B; Maduropeptin chromophore B; Antibiotic C 1027 chromophore analog
EINECS	Contact for details

Quality Control

Our Maduropeptin B is produced and handled under strict quality protocols to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot is accompanied by comprehensive analytical data, including HPLC purity and structural confirmation via spectroscopic methods. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.