Description

Luzopeptin CAS NO 134688-25-8 is a potent, naturally occurring cyclic peptide antibiotic complex isolated from *Actinomadura luzonensis*. This compound is of significant interest in biochemical and pharmaceutical research due to its unique mechanism of action, primarily functioning as a DNA intercalator and topoisomerase inhibitor. It is a critical research-grade material for scientists and developers in oncology research, molecular biology, and the development of novel chemotherapeutic agents.

Application

• Oncology Research: As a DNA-binding agent, it is used to study mechanisms of cytotoxicity, apoptosis, and the inhibition of topoisomerase I and II in various cancer cell lines.
• Biochemical Tool Compound: Serves as a standard or probe in enzymatic assays to investigate DNA replication, transcription, and repair processes.
• Antimicrobial Studies: Used in research to explore its spectrum of activity against Gram-positive bacteria and its underlying antibiotic mechanisms.
• Pharmaceutical Development: Acts as a lead compound or reference standard in the discovery and development of new anticancer and antimicrobial therapeutics.
• Academic & Institutional Research: Employed in university and government laboratories for fundamental studies in chemical biology and medicinal chemistry.

Basic Information

Product Name	Luzopeptin
CAS No.	134688-25-8
Molecular Formula	C54H62N12O16
Molecular Weight	1111.15 g/mol
Synonyms	Luzopeptin A; Luzopeptin C; Antibiotic BBM-928; Antibiotic BBM 928A; BBM-928; BBM 928A; NSC-650426; NSC 650426
EINECS	Contact for details

Quality Control

Our Luzopeptin is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and reliability for research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity determination and spectroscopic methods for structural confirmation. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, purity, and other critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry, controlled environment. Due to its hygroscopic nature, the product should be handled under anhydrous conditions and allowed to equilibrate to room temperature in a desiccator before opening to prevent moisture absorption.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in DMSO, DMF; sparingly soluble in methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.