Description

3-(Trifluoromethyl)-1H-Indene is a versatile fluorinated indene derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the unique reactivity and electronic properties imparted by the trifluoromethyl group, enabling the creation of complex molecules with enhanced stability and performance. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries, particularly for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, especially in central nervous system (CNS) and anti-inflammatory therapies.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, where the CF₃ group improves biological activity and environmental persistence.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Functional Material Precursor: Employed in the synthesis of organic semiconductors, liquid crystals, and other advanced electronic materials.
• Fluorine Chemistry Research: A valuable reagent for studying the introduction and effects of fluorine atoms in organic frameworks.
• Custom Synthesis Building Block: Provides a versatile scaffold for contract research organizations (CROs) and fine chemical companies performing bespoke synthesis.

Basic Information

Product Name	3-(Trifluoromethyl)-1H-Indene
CAS No.	134391-57-4
Molecular Formula	C₁₀H₇F₃
Molecular Weight	184.16 g/mol
Synonyms	1H-Indene, 3-(trifluoromethyl)-; 3-(Trifluoromethyl)indene; 3-Trifluoromethyl-1H-indene; 3-Trifluoromethylindene; 3-CF3-1H-Indene; 3-(Trifluoromethyl)indane (common misnomer); α,α,α-Trifluoro-m-toluidine cyclization product (process-related)
EINECS	Contact for details

Quality Control

Our 3-(Trifluoromethyl)-1H-Indene is produced under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and fluorides. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.