Description

4-Bromo-2,5-Difluorobenzonitrile is a high-purity, multi-functional aromatic intermediate of significant importance in advanced organic synthesis. Its unique structure, featuring bromine, fluorine, and nitrile substituents, makes it a versatile building block for constructing complex molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Key pharmaceutical intermediate in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders.
• Critical building block for agrochemical research, used to develop new herbicides, fungicides, and insecticides with enhanced efficacy.
• Precursor in material science for creating specialized polymers, liquid crystals, and organic electronic materials.
• Versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Intermediate for synthesizing custom ligands and catalysts used in cross-coupling reactions and other catalytic processes.
• Starting material for the development of dyes and pigments with specific optical properties.

Basic Information

Product Name	4-Bromo-2,5-Difluorobenzonitrile
CAS No.	133541-45-4
Molecular Formula	C7H2BrF2N
Molecular Weight	218.00 g/mol
Synonyms	2,5-Difluoro-4-bromobenzonitrile; 4-Bromo-2,5-difluorobenzene carbonitrile; Benzonitrile, 4-bromo-2,5-difluoro-; 133541-45-4; 4-Bromo-2,5-difluorophenyl cyanide
EINECS	Contact for details

Quality Control

Our 4-Bromo-2,5-Difluorobenzonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistent performance. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for all shipments to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.