Description

1-(4-Methanesulfonamidophenoxy)-3-(n-Methyl-3,4-Dichlorophenylethylamino)-2-Propanol is a specialized organic compound with a complex molecular structure designed for targeted pharmacological activity. This compound matters as a key intermediate or active pharmaceutical ingredient (API) in the development of advanced therapeutic agents, particularly those targeting adrenergic receptors. It is primarily needed by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic research institutions focused on cardiovascular and metabolic drug discovery.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel β-adrenergic receptor antagonists (β-blockers).
• Cardiovascular Drug Research: Used in preclinical studies for developing compounds aimed at treating hypertension, angina, and arrhythmias.
• Metabolic Disorder Research: Investigated for potential applications in drug candidates targeting metabolic syndromes.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis for creating complex, high-value molecules with specific stereochemistry.
• Biochemical Tool Compound: Utilized in pharmacological assays to study receptor binding and signal transduction pathways.
• Reference Standard: Acts as a certified reference material (CRM) for quality control and analytical method development in pharmaceutical manufacturing.

Basic Information

Product Name	1-(4-Methanesulfonamidophenoxy)-3-(n-Methyl-3,4-Dichlorophenylethylamino)-2-Propanol
CAS No.	133229-23-9
Molecular Formula	C19H24Cl2N2O4S
Molecular Weight	447.37 g/mol
Synonyms	1-(4-Methanesulfonamidophenoxy)-3-(N-Methyl-3,4-dichlorophenylethylamino)-2-propanol; 3,4-Dichloro-N-[2-hydroxy-3-[(4-methanesulfonamidophenoxy]propyl]-N-methylphenethylamine; Carazolol sulfonamide derivative; β-blocker intermediate 133229-23-9; CAS 133229-23-9; 1-[4-(Methylsulfonylamino)phenoxy]-3-[N-methyl-2-(3,4-dichlorophenyl)ethylamino]-2-propanol
EINECS	Contact for details

Quality Control

Our 1-(4-Methanesulfonamidophenoxy)-3-(n-Methyl-3,4-Dichlorophenylethylamino)-2-Propanol is manufactured under strict quality management systems. All batches undergo rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure compliance with research and pharmaceutical-grade standards. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.