Description

2-Fluoro-6-(trifluoromethyl)benzonitrile is a versatile fluorinated aromatic nitrile building block of significant interest in advanced organic synthesis. Its value lies in the synergistic reactivity of the nitrile and fluorine substituents, enabling precise molecular construction for high-value compounds. This intermediate is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoromethyl and fluorine groups enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for specialized ligands in catalysis and as a building block for functional materials.
• Fluorinated Liquid Crystal Research: Employed in the synthesis of novel fluorinated aromatic cores for advanced display materials.
• Organic Electronic Materials: Investigated as a component in the development of semiconductors and other electronic materials due to its electron-withdrawing properties.

Basic Information

Product Name	2-Fluoro-6-(trifluoromethyl)benzonitrile
CAS No.	133116-83-3
Molecular Formula	C8H3F4N
Molecular Weight	189.11 g/mol
Synonyms	2-Fluoro-α,α,α-trifluoro-o-tolunitrile; 2-Cyano-3-fluorobenzotrifluoride; 2-Fluoro-6-(trifluoromethyl)phenyl cyanide; 6-Fluoro-2-(trifluoromethyl)benzonitrile; o-Fluoro-α,α,α-trifluorotoluonitrile; Benzonitrile, 2-fluoro-6-(trifluoromethyl)-; 2-Fluoro-α,α,α-trifluorobenzyl cyanide
EINECS	Contact for details

Quality Control

Our 2-Fluoro-6-(trifluoromethyl)benzonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for research and process development. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.