Description

3-(tert-Butylamino)-1-(3,4-Dihydroxy-6-Fluorophenoxy)-2-Propanol is a specialized synthetic intermediate featuring a fluorinated catechol moiety linked to a propanolamine structure. This compound matters for its role as a key building block in the development of advanced pharmaceutical agents, particularly β-adrenergic receptor ligands and other bioactive molecules. Pharmaceutical R&D laboratories and fine chemical manufacturers need this high-purity intermediate to support the synthesis of novel therapeutic candidates.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of β-blockers and other cardiovascular or neurological drug candidates.
• Biochemical Research: Used as a reference standard or a probe in studying adrenergic receptor interactions and signal transduction pathways.
• Fine Chemical Synthesis: Serves as a versatile building block for constructing complex molecules with fluorinated aromatic systems for material science applications.
• Active Pharmaceutical Ingredient (API) Development: Employed in the research and process development stages for new chemical entities (NCEs).

Basic Information

Product Name	3-(tert-Butylamino)-1-(3,4-Dihydroxy-6-Fluorophenoxy)-2-Propanol
CAS No.	132178-19-9
Molecular Formula	C₁₃H₂₀FNO₄
Molecular Weight	273.30 g/mol
Synonyms	1-(3,4-Dihydroxy-6-fluorophenoxy)-3-[(1,1-dimethylethyl)amino]-2-propanol; 6-Fluoro-3,4-dihydroxyphenoxypropanolamine tert-butyl derivative; 3-(tert-Butylamino)-1-(6-fluoro-3,4-dihydroxyphenoxy)-2-propanol; 6-Fluorodopamine propanolamine derivative; (RS)-1-(6-Fluoro-3,4-dihydroxyphenoxy)-3-(tert-butylamino)propan-2-ol; Fluorocatechol propanolamine intermediate; tert-Butylaminofluorocatechol propanol
EINECS	Contact for details

Quality Control

Our 3-(tert-Butylamino)-1-(3,4-Dihydroxy-6-Fluorophenoxy)-2-Propanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D and fine chemical synthesis. Certificates of Analysis (COA) documenting full specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.