Description

Delta14 -Desonide CAS NO 131918-67-7 is a high-purity synthetic corticosteroid, specifically a non-halogenated derivative of prednisolone. This compound is valued for its potent anti-inflammatory and immunosuppressive properties, making it a critical intermediate in advanced pharmaceutical synthesis. It is primarily required by manufacturers in the pharmaceutical industry for the development and production of topical dermatological creams, ointments, and other therapeutic formulations targeting inflammatory skin conditions.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potent topical corticosteroids for anti-inflammatory medications.
• Dermatological Formulations: Used in the research and production of creams, ointments, and lotions for treating eczema, psoriasis, and contact dermatitis.
• API Development: Serves as a critical starting material or intermediate in the development of new Active Pharmaceutical Ingredients (APIs) with glucocorticoid receptor activity.
• Veterinary Medicine: Employed in the formulation of anti-inflammatory treatments for skin conditions in animals.
• Biochemical Research: Used as a reference standard or tool compound in pharmacological studies investigating steroid receptor pathways and mechanisms of inflammation.

Basic Information

Product Name	Delta14 -Desonide
CAS No.	131918-67-7
Molecular Formula	C24H32O6
Molecular Weight	416.51 g/mol
Synonyms	9α-Fluoro-11β,16α,17,21-tetrahydroxypregna-1,4-diene-3,20-dione cyclic 16,17-acetal with acetone; Desonide; 11β,16α,17,21-Tetrahydroxy-9α-fluoropregna-1,4-diene-3,20-dione cyclic 16,17-acetal with acetone; Prednacinolone; Tridesilon; Sterax; Apolar; Hydroxyprednisolone acetonide
EINECS	Contact for details

Quality Control

Our Delta14 -Desonide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, residual solvent analysis, and identification by IR and NMR spectroscopy, to ensure it meets stringent pharmaceutical-grade specifications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance with relevant guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.5% Any single impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.