Description

Diisopropylethylamine Trihydrofluoride is a specialized fluorinating agent and a stable, solid equivalent of hydrogen fluoride. This compound is valued for its ability to safely and efficiently introduce fluoride ions in demanding synthetic processes, offering a more controlled and less hazardous alternative to gaseous or aqueous HF. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for nucleophilic fluorination and deprotection reactions.

Application

• Pharmaceutical Synthesis: A key reagent for the selective fluorination of active pharmaceutical ingredients (APIs) and advanced intermediates.
• Agrochemical Manufacturing: Used in the synthesis of fluorinated pesticides and herbicides to enhance their biological activity and stability.
• Petroleum Catalyst Preparation: Employed in the preparation and regeneration of fluorinated solid acid catalysts, such as those used in alkylation processes.
• Organic Synthesis: Facilitates deprotection of silyl ethers (e.g., TBDMS, TIPS) and serves as a mild source of fluoride ion for various coupling and functional group transformations.
• Electrolyte Additive: Investigated as an additive in lithium-ion battery electrolytes to improve SEI (Solid Electrolyte Interphase) stability and performance.
• Material Science: Used in the surface treatment and etching of silicon-based materials in semiconductor research.

Basic Information

Product Name	Diisopropylethylamine Trihydrofluoride
CAS No.	131600-43-6
Molecular Formula	C8H21N · 3HF
Molecular Weight	221.26 g/mol
Synonyms	DIPEA Trihydrofluoride; Hünig's Base Trihydrofluoride; N,N-Diisopropylethylamine Trihydrofluoride; N-Ethyldiisopropylamine Trihydrofluoride; DIPEA·3HF; EtNiPr2·3HF; Fluoride/strong alkali; Trihydrofluoride salt of DIPEA
EINECS	Contact for details

Quality Control

Our Diisopropylethylamine Trihydrofluoride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for research and industrial-scale applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (Titration)	≥ 98.0 %
Water Content (KF)	≤ 1.0 %
Heavy Metals (as Pb)	≤ 10 ppm
Residue on Ignition	≤ 0.1 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.