Description

Benzeneacetonitrile, Alpha,4-Difluoro- (9Ci) is a specialized fluorinated organic nitrile building block. This high-value intermediate is critical for introducing difluoromethyl and cyano functional groups into complex molecular architectures. It is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients. Its unique structure makes it a key precursor for compounds requiring specific fluorine substitution patterns.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides, fungicides, and insecticides where the difluoro and nitrile groups enhance biological activity and stability.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated compounds used in electronic displays and organic light-emitting diodes (OLEDs).
• Fluorinated Polymer Research: Employed in the development of specialty polymers with improved chemical resistance, thermal stability, and unique surface properties.
• Chemical Biology & Probe Development: Utilized in creating molecular probes and tags for studying biological processes and enzyme mechanisms.
• Custom Synthesis & Contract Manufacturing: A valuable reagent for fine chemical and custom synthesis houses serving the life sciences sector.

Basic Information

Item	Detail
Product Name	Benzeneacetonitrile, Alpha,4-Difluoro- (9Ci)
CAS No.	130754-18-6
Molecular Formula	C8H5F2N
Molecular Weight	153.13 g/mol
Synonyms	2-(4-Fluorophenyl)-2-fluoroacetonitrile; 4-Fluoro-α-fluorophenylacetonitrile; α,4-Difluorobenzeneacetonitrile; (4-Fluorophenyl)(fluoro)acetonitrile; 2-Fluoro-2-(4-fluorophenyl)acetonitrile; 4-Fluoro-α-fluorobenzeneacetonitrile; 130754-18-6 (CAS)
EINECS	Contact for details

Quality Control

Our Benzeneacetonitrile, Alpha,4-Difluoro- (9Ci) is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR, IR, and GC-MS. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.