Description

Vorozole is a potent, non-steroidal, third-generation aromatase inhibitor, a key compound in advanced pharmaceutical research and development. Its primary value lies in its selective inhibition of the aromatase enzyme, which is critical for the biosynthesis of estrogens. This makes it an essential research chemical for oncology studies, particularly in the investigation of hormone-dependent cancers such as breast cancer. Researchers and pharmaceutical developers in the global life sciences sector rely on high-purity Vorozole CAS NO 129731-10-8 for preclinical and clinical research applications.

Application

• Oncology Research: A key reference standard and active pharmaceutical ingredient (API) in the study of hormone-responsive breast cancer.
• Enzyme Inhibition Studies: Used in biochemical assays to investigate the mechanism and kinetics of aromatase (CYP19) inhibition.
• Pharmaceutical Development: Serves as a critical intermediate or model compound in the R&D of novel anticancer therapeutics.
• Preclinical & Clinical Trials: Employed as a benchmark in comparative efficacy and safety studies for new aromatase inhibitors.
• Academic Research: Utilized in university and institutional labs for endocrinology and cancer biology research projects.
• Reference Standard: Acts as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	Vorozole
CAS No.	129731-10-8
Molecular Formula	C₁₇H₁₉N₅
Molecular Weight	293.37 g/mol
Synonyms	6-[(4-Chlorophenyl)(1H-1,2,4-triazol-1-yl)methyl]-1-methyl-1H-benzotriazole; R 76713; R-76713; Vorozolum; (+)-Vorozole; (R)-Vorozole; CGS 16949A; CGS-16949A
EINECS	Contact for details

Quality Control

Our Vorozole is manufactured under strict quality management systems to ensure the highest standards of purity and consistency, suitable for research and development purposes. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry guidelines to support our global clientele in pharmaceutical and academic research.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.