Description

7-o-(2,6-Dideoxy-2-Fluro-α-Talopyranosyl)Adriamycinol is a fluorinated glycoside derivative of the anthracycline class, representing a key intermediate in advanced pharmaceutical synthesis. This compound is valued for its role in the development of novel chemotherapeutic agents, offering a pathway to more targeted and potent drug candidates. It is primarily required by research institutions and pharmaceutical manufacturers engaged in oncology drug discovery and the synthesis of next-generation anthracycline antibiotics.

Application

• Pharmaceutical Intermediate: A critical building block in the research and synthesis of novel anthracycline-based chemotherapeutic drugs.
• Oncology Research: Used in biochemical and pharmacological studies to investigate structure-activity relationships (SAR) and mechanisms of action against cancer cell lines.
• API Development: Serves as a precursor in the development of Active Pharmaceutical Ingredients (APIs) with potentially improved efficacy or reduced cardiotoxicity.
• Academic & Institutional Research: Employed in university and contract research organization (CRO) laboratories for exploratory medicinal chemistry projects.
• Process Chemistry: Utilized in scaling up synthetic routes for fluorinated glycoside compounds under Good Manufacturing Practice (GMP) conditions.

Basic Information

Product Name	7-o-(2,6-Dideoxy-2-Fluro-α-Talopyranosyl)Adriamycinol
CAS No.	129051-72-5
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	7-O-(2,6-Dideoxy-2-fluoro-α-L-talopyranosyl)adriamycinol; Fluorinated Adriamycinol Glycoside; 2'-Fluoro-4'-epi-daunorubicin derivative; 7-O-(2,6-Dideoxy-2-fluoro-α-talopyranosyl)doxorubicinol; 129051-72-5; 7-O-(2,6-Dideoxy-2-fluoro-α-L-talopyranosyl)-13-dihydrocarminomycin
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for research and pharmaceutical intermediates. We employ advanced analytical techniques, including HPLC and NMR, to verify identity and purity. Certificates of Analysis (COA) are available upon request, detailing batch-specific results. Our commitment to quality supports reliable and reproducible outcomes in your critical research and development workflows.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) to minimize oxidation and degradation. Keep the container in a cool, dry, and well-ventilated area, away from incompatible materials.

Specification

Item	Specification
Appearance	Red to orange-red powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Individual impurity ≤ 2.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.