Description

2,4-Dichloro-5-Fluorobenzonitrile is a versatile halogenated benzonitrile derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its unique substitution pattern, which provides multiple reactive sites for constructing complex molecular architectures. This high-purity intermediate is essential for research and production in the pharmaceutical and agrochemical industries, where it is used to develop active ingredients and novel compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules containing fluorinated and chlorinated aromatic systems.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, leveraging its halogenated structure for bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in metal-catalyzed cross-coupling reactions.
• Material Science Research: Employed in the synthesis of functionalized polymers and liquid crystals where specific halogen interactions are required.
• Custom Synthesis and R&D: A valuable scaffold for medicinal chemistry and discovery chemistry programs in contract research organizations (CROs).

Basic Information

Product Name	2,4-Dichloro-5-Fluorobenzonitrile
CAS No.	128593-93-1
Molecular Formula	C7H2Cl2FN
Molecular Weight	190.00 g/mol
Synonyms	5-Fluoro-2,4-dichlorobenzonitrile; 2,4-Dichloro-5-fluorobenzene carbonitrile; 2,4-Dichloro-5-fluorophenyl cyanide; Benzonitrile, 2,4-dichloro-5-fluoro-; 128593-93-1; 5-Fluoro-2,4-dichlorobenzene-1-carbonitrile
EINECS	Contact for details

Quality Control

Our 2,4-Dichloro-5-Fluorobenzonitrile is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards and can provide material suitable for GMP applications upon request, ensuring reliable supply and traceability for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be stored away from direct light exposure.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.