Description

Altromycin B is a potent ansamycin-class antibiotic compound with significant research and development value. Its unique mechanism of action makes it a critical tool for studying bacterial resistance and developing novel therapeutic agents. This high-purity compound is essential for pharmaceutical R&D, academic research, and biotechnology applications focused on infectious diseases and antibiotic discovery.

Application

• Pharmaceutical Research & Development: Serves as a key reference standard and active pharmaceutical ingredient (API) intermediate in the development of new antibiotic therapies.
• Mechanistic Studies: Used in biochemical and microbiological research to investigate the inhibition of bacterial RNA polymerase and mechanisms of antimicrobial action.
• Academic Research: Employed in university and institutional labs for studies on ansamycin antibiotics, structure-activity relationships (SAR), and bacterial genetics.
• Biotechnology Applications: Utilized in screening assays and high-throughput platforms to discover new compounds with similar or enhanced antimicrobial profiles.
• Quality Control & Analytical Standards: Acts as a certified reference material (CRM) for the identification and quantification of Altromycin B in raw materials and finished products.

Basic Information

Product Name	Altromycin B
CAS No.	128461-00-7
Molecular Formula	C39H48N2O11
Molecular Weight	720.81 g/mol
Synonyms	BMY-28438; Antibiotic BMY 28438; U-62162; (2S)-2-[(3S,5R,6S,8R,9S,10R,11S,12S,13R,14S,16R)-11-[(2R,3S,4S,5S,6R)-4-Amino-3,5-dihydroxy-6-methyloxan-2-yl]oxy-6-[(2S,3S,4S,6R)-3,4-dihydroxy-6-methyloxan-2-yl]oxy-9,16-dihydroxy-8,10,12,14-tetramethyl-4,17-dioxo-3-propan-2-yl-2-oxa-15-azabicyclo[12.3.1]octadeca-1(18),14,16-trien-13-yl]-2-hydroxypropanoic acid
EINECS	Contact for details

Quality Control

Our Altromycin B is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by spectroscopic methods (IR, NMR), and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines
Assay	90.0% - 110.0% (on anhydrous basis)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.