Description

(3R)-Hydroxyquinine is a high-purity, stereochemically defined derivative of the natural alkaloid quinine. This compound serves as a critical chiral building block and analytical standard in advanced organic synthesis and pharmaceutical research. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries who require high-fidelity chiral intermediates for the development of active ingredients and complex molecules.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of novel therapeutic agents and active pharmaceutical ingredients (APIs).
• Asymmetric Catalysis: Utilized as a chiral ligand or catalyst in enantioselective synthesis to control stereochemistry.
• Analytical Standard: Serves as a certified reference material (CRM) for method development, validation, and quality control in HPLC and LC-MS analysis.
• Biochemical Research: Used as a tool compound in pharmacological studies to investigate biological pathways and receptor interactions.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex natural product analogs and specialty chemicals.

Basic Information

Product Name	(3R)-Hydroxyquinine
CAS No.	128241-59-8
Molecular Formula	C20H24N2O2
Molecular Weight	324.42 g/mol
Synonyms	(3R)-Hydroxyquinine; (R)-3-Hydroxyquinine; 3(R)-Hydroxyquinine; Quinidine, 3-hydroxy-; 3-Hydroxyquinine (3R-isomer); (8α,9R)-6'-Methoxycinchonan-3,9-diol; 3-Hydroxyquinidine
EINECS	Contact for details

Quality Control

Our (3R)-Hydroxyquinine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.