Description

2-Fluoronitrobenzene is a versatile fluorinated aromatic intermediate essential for advanced organic synthesis. Its unique structure, featuring both an electron-withdrawing nitro group and a fluorine atom, makes it a critical building block for creating complex molecules with tailored properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of fluorinated active pharmaceutical ingredients (APIs), including potential candidates for CNS drugs and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the development of novel herbicides, pesticides, and fungicides where the fluorine atom enhances biological activity and environmental stability.
• Liquid Crystal & Electronic Materials: Serves as a building block for fluorinated liquid crystals and organic semiconductors used in display technologies and electronic devices.
• Dye & Pigment Manufacturing: Intermediate for producing specialty dyes and pigments where fluorine substitution improves lightfastness and color properties.
• Cross-Coupling Reactions: A valuable substrate in Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl structures.
• Organic Synthesis Research: Employed in academic and industrial R&D for studying nucleophilic aromatic substitution reactions and developing new fluorination methodologies.

Basic Information

Item	Details
Product Name	2-Fluoronitrobenzene
CAS No.	127723-77-7
Molecular Formula	C6H4FNO2
Molecular Weight	141.10 g/mol
Synonyms	1-Fluoro-2-nitrobenzene; o-Fluoronitrobenzene; 2-Nitrofluorobenzene; ortho-Fluoronitrobenzene; ONFB; Fluorobenzene, 2-nitro-; Benzene, 1-fluoro-2-nitro-
EINECS	Contact for details

Quality Control

Our 2-Fluoronitrobenzene is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee it meets your specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and organic solvents. Recommended storage temperature is between 15°C and 25°C. Keep container tightly sealed when not in use to prevent moisture absorption and volatilization.

Specification

Item	Specification
Appearance	Clear, pale yellow to yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Purity (HPLC)	≥ 97.5%
Water Content (KF)	≤ 0.5%
Density (at 20°C)	~1.33 g/cm³
Boiling Point	~205-207 °C
Refractive Index (n20D)	~1.535 - 1.540

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.