Description

2-Chloro-3,4,5,6-Tetrafluorobenzonitrile is a highly fluorinated aromatic nitrile building block, distinguished by its unique halogen substitution pattern. This compound is valued for its role as a critical intermediate in the synthesis of advanced materials and active pharmaceutical ingredients (APIs), where its structure imparts desirable properties like enhanced stability and lipophilicity. It is primarily sought by research and development teams, as well as production chemists, in the agrochemical, pharmaceutical, and specialty chemical industries for constructing complex molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in fluorinated bioactive molecules.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where the fluorinated aromatic core enhances efficacy and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated components in electronic display and lighting technologies.
• Polymer & Resin Modification: Incorporated to create specialty polymers with improved chemical resistance, thermal stability, and surface properties.
• Organic Synthesis & Catalysis: Employed in cross-coupling reactions and as a precursor for ligands in catalytic systems.
• Research & Development: Utilized in academic and industrial R&D for exploring new chemical entities and reaction pathways.

Basic Information

Product Name	2-Chloro-3,4,5,6-Tetrafluorobenzonitrile
CAS No.	126817-44-5
Molecular Formula	C7ClF4N
Molecular Weight	213.53 g/mol
Synonyms	2-Chloro-3,4,5,6-tetrafluorobenzene carbonitrile; 2-Chlorotetrafluorobenzonitrile; Benzonitrile, 2-chloro-3,4,5,6-tetrafluoro-; 3,4,5,6-Tetrafluoro-2-chlorobenzonitrile; 2-Chloro-3,4,5,6-tetrafluorophenyl cyanide; TFB-CN (common abbreviation); Tetrafluorochlorobenzonitrile
EINECS	Contact for details

Quality Control

Our 2-Chloro-3,4,5,6-Tetrafluorobenzonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure high purity and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP principles where applicable to support our customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and fluorides. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.