Description

14-Quinaldinoyloxydaunorubicin is a chemically modified derivative of the anthracycline antibiotic daunorubicin, designed for enhanced pharmacological properties. This compound is of significant interest in advanced pharmaceutical research and development, particularly in the exploration of novel anticancer therapeutics. It is primarily utilized by research institutions, pharmaceutical R&D departments, and biotechnology companies engaged in oncology drug discovery and preclinical studies.

Application

• Pharmaceutical Research & Development: Serves as a key intermediate or active pharmaceutical ingredient (API) in the synthesis and investigation of next-generation anthracycline-based chemotherapeutic agents.
• Oncology Drug Discovery: Used in preclinical studies to evaluate efficacy, mechanism of action, and structure-activity relationships (SAR) against various cancer cell lines.
• Biochemical Research: Employed as a tool compound to study DNA intercalation, topoisomerase II inhibition, and other biological pathways relevant to anthracycline activity.
• Reference Standard: Acts as a high-purity analytical standard for quality control and method development in pharmaceutical analysis using techniques like HPLC and LC-MS.

Basic Information

Product Name	14-Quinaldinoyloxydaunorubicin
CAS No.	126657-27-0
Molecular Formula	C36H35N3O11
Molecular Weight	685.68 g/mol
Synonyms	14-O-(Quinaldinoyl)daunorubicin; 14-Quinaldinoyloxydaunomycin; Daunorubicin 14-quinaldinate; 14-O-(2-Quinolinecarbonyl)daunorubicin; 14-Quinaldinoyloxy-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-5,12-naphthacenedione; (8S,10S)-8-Acetyl-10-[(2S,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-6,8,11-trihydroxy-1-methoxy-9,10-dihydro-7H-tetracene-5,12-dione 14-(quinoline-2-carboxylate)
EINECS	Contact for details

Quality Control

Our 14-Quinaldinoyloxydaunorubicin is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to relevant standards for research-grade chemicals, with specifications tailored to meet the stringent requirements of pharmaceutical R&D.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Orange to red powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.