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(R)-(-)-1,1'-Binaphthol-2,2'-Bis(Trifluoromethanesulfonate) CAS NO 126613-06-7


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CAS No.:126613-06-7

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

(R)-(-)-1,1'-Binaphthol-2,2'-Bis(Trifluoromethanesulfonate) is a high-value, chiral chemical intermediate and ligand precursor essential for asymmetric synthesis. This compound matters because it serves as a versatile building block for constructing complex, enantiomerically pure molecules, enabling the production of advanced pharmaceuticals and specialty chemicals. It is critically needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for applications requiring precise stereochemical control.

Application

  • Asymmetric Catalysis: As a precursor to BINOL-derived chiral phosphoric acids and other organocatalysts for enantioselective transformations.
  • Pharmaceutical Intermediate: Key building block in the synthesis of chiral active pharmaceutical ingredients (APIs) and complex natural products.
  • Ligand Synthesis: Used to prepare sophisticated chiral ligands for transition metal catalysis, such as palladium-catalyzed cross-coupling reactions.
  • Material Science Research: Employed in the development of chiral polymers, liquid crystals, and molecular recognition systems.
  • Agrochemical Synthesis: Intermediate for creating enantiomerically pure herbicides, fungicides, and plant growth regulators.
  • Academic & Industrial R&D: A fundamental reagent for methodological development in organic and medicinal chemistry.

Basic Information

Product Name (R)-(-)-1,1'-Binaphthol-2,2'-Bis(Trifluoromethanesulfonate)
CAS No. 126613-06-7
Molecular Formula C₂₂H₁₂F₆O₆S₂
Molecular Weight 574.45 g/mol
Synonyms (R)-BINOL-Bis(Triflate); (R)-1,1'-Bi-2-naphthol Bis(Trifluoromethanesulfonate); (R)-(-)-1,1'-Binaphthalene-2,2'-diyl Bis(Trifluoromethanesulfonate); (R)-BINOL Ditriflate; (R)-2,2'-Bis(trifluoromethanesulfonyloxy)-1,1'-binaphthyl; (R)-BINOL-OTf₂; (R)-BINOL Triflate; (R)-H8-BINOL Ditriflate (related derivative)
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Quality Control

Our (R)-(-)-1,1'-Binaphthol-2,2'-Bis(Trifluoromethanesulfonate) is manufactured under strict quality systems to ensure batch-to-batch consistency and high enantiomeric purity. All products undergo rigorous analytical testing, including HPLC, NMR, and chiral analysis, to ensure compliance with customer specifications and industry standards. A comprehensive Certificate of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for prolonged storage or after opening to prevent decomposition.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 98.0%
Enantiomeric Excess (Chiral HPLC) ≥ 99.0%
Water Content (KF) ≤ 0.5%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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