Description

4-Bromo-2,3-Difluorobenzonitrile is a high-purity, multi-functional aromatic intermediate of significant importance in advanced organic synthesis. Its unique halogenated and nitrile-substituted structure makes it a valuable building block for constructing complex molecular architectures. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging the fluorine and bromine atoms for enhanced bioactivity and environmental stability.
• Liquid Crystal & OLED Material Precursor: Serves as a critical starting material for synthesizing fluorinated aromatic compounds used in electronic displays and organic light-emitting diodes.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and Buchwald-Hartwig amination reactions, enabling the formation of new carbon-carbon and carbon-heteroatom bonds.
• Functional Material Research: Employed in academic and industrial R&D for creating novel polymers, ligands for catalysis, and specialty chemicals with tailored properties.

Basic Information

Product Name	4-Bromo-2,3-Difluorobenzonitrile
CAS No.	126163-58-4
Molecular Formula	C7H2BrF2N
Molecular Weight	218.00 g/mol
Synonyms	2,3-Difluoro-4-bromobenzonitrile; 4-Bromo-2,3-difluorobenzene carbonitrile; Benzonitrile, 4-bromo-2,3-difluoro-; 126163-58-4; 4-Br-2,3-F2-PhCN
EINECS	Contact for details

Quality Control

Our 4-Bromo-2,3-Difluorobenzonitrile is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and industry best practices.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	72 - 76 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.