Description

2,3-Difluoro-4-Cyanophenetole is a high-purity fluorinated aromatic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily needed by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), liquid crystal materials, and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of fluorinated drug candidates, including kinase inhibitors and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and pesticides, where the fluorine atoms enhance biological activity and metabolic stability.
• Liquid Crystal Materials: Serves as a building block for fluorinated liquid crystal molecules used in display technologies (LCDs).
• Organic Electronic Materials: Employed in the research and production of materials for organic light-emitting diodes (OLEDs) and semiconductors.
• Advanced Polymer Chemistry: Acts as a monomer or modifier to introduce fluorine and cyano groups into specialty polymers, improving their chemical resistance and thermal properties.
• Chemical Research & Development: A versatile reagent for constructing complex aromatic systems in academic and industrial research laboratories.

Basic Information

Product Name	2,3-Difluoro-4-Cyanophenetole
CAS No.	126162-96-7
Molecular Formula	C9H7F2NO
Molecular Weight	183.16 g/mol
Synonyms	4-Cyano-2,3-difluorophenetole; 1-Ethoxy-2,3-difluoro-4-cyanobenzene; 2,3-Difluoro-4-ethoxybenzonitrile; 2,3-Difluoro-4-cyanophenetole; 4-Ethoxy-2,3-difluorobenzonitrile; 2,3-Difluoro-4-cyanophenyl ethyl ether; 2,3-Difluoro-4-(ethoxy)benzonitrile; Benzene, 1-cyano-2,3-difluoro-4-ethoxy-
EINECS	Contact for details

Quality Control

Our 2,3-Difluoro-4-Cyanophenetole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, impurity profile, and physical characteristics are provided with every shipment to guarantee consistent quality and traceability for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.