Description

14-o-Palmitoylhydroxyrubicin CAS NO 124622-11-3 is a chemically modified derivative of the anthracycline class, designed to enhance lipophilicity and potentially alter its pharmacokinetic profile. This compound is of significant interest for advanced pharmaceutical research and development, particularly in the field of targeted drug delivery systems. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel oncology therapeutics and prodrug formulations.

Application

• Pharmaceutical Research: Key intermediate or active moiety in the development of novel anticancer agents and prodrugs.
• Prodrug Synthesis: Utilized for creating lipophilic prodrugs aimed at improving bioavailability and tumor targeting.
• Drug Delivery Systems: Incorporated into liposomal, nanoparticle, or micellar formulations for enhanced therapeutic efficacy.
• Biochemical Studies: Serves as a tool compound in studies investigating structure-activity relationships (SAR) of anthracycline derivatives.
• Preclinical Development: Used in in vitro and in vivo models to evaluate pharmacokinetics, metabolism, and antitumor activity.

Basic Information

Product Name	14-o-Palmitoylhydroxyrubicin
CAS No.	124622-11-3
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	14-O-Palmitoylhydroxyrubicin; 14-Palmitoylhydroxyrubicin; Hydroxyrubicin 14-palmitate; Doxorubicin 14-palmitate derivative; 14-O-Hexadecanoylhydroxyrubicin; Palmitoyl ester of hydroxyrubicin; Anthracycline palmitate derivative
EINECS	Contact for details

Quality Control

Our 14-o-Palmitoylhydroxyrubicin is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatographic purity analysis and identity confirmation, to ensure it meets high-purity standards suitable for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and related substances is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	Orange to red solid
Identification (HPLC/IR)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.