Description

Dynemicin A is a potent enediyne antitumor antibiotic renowned for its unique molecular architecture and mechanism of action. Its core value lies in its ability to induce DNA strand scission through a Bergman cycloaromatization, making it a compound of significant interest in advanced pharmaceutical research and development. This product is essential for researchers in oncology drug discovery, molecular biology, and synthetic chemistry who are investigating novel therapeutic agents and DNA-interactive compounds. CAS No. 124412-57-3.

Application

• Anticancer Research: Serves as a critical reference standard and active pharmaceutical ingredient (API) in the development of novel chemotherapeutic agents targeting various cancers.
• Molecular Biology Studies: Used as a biochemical tool to study DNA damage and repair mechanisms, apoptosis, and cell cycle regulation.
• Chemical Synthesis & Medicinal Chemistry: Acts as a complex molecular scaffold and intermediate for the synthesis of analogs with modified potency and selectivity profiles.
• Mechanism of Action (MoA) Investigation: Employed in pharmacological studies to elucidate the precise biochemical pathways of enediyne antibiotics.
• Academic & Institutional Research: Utilized in university and government laboratories for fundamental research in bioorganic chemistry and pharmacology.

Basic Information

Product Name	Dynemicin A
CAS No.	124412-57-3
Molecular Formula	C30H28N2O8
Molecular Weight	544.56 g/mol
Synonyms	Dynemicin A; Antibiotic Dynemicin A; 10,13-Epoxy-16-methyl-7,9,11,15,17-pentaazapentacyclo[11.7.0.02,10.04,8.015,19]icosa-1(13),2,4(8),5,14,16,18-heptaene-3,6,12,20-tetrone; (1S,5R,6R,7S,8R,13S,14R,16R,19S)-10,13-Epoxy-16-methyl-7,9,11,15,17-pentaazapentacyclo[11.7.0.02,10.04,8.015,19]icosa-1(13),2,4(8),5,14,16,18-heptaene-3,6,12,20-tetrone
EINECS	Contact for details

Quality Control

Our Dynemicin A is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles, typically determined by advanced analytical techniques such as HPLC and NMR. We adhere to relevant quality guidelines to support our global clientele in pharmaceutical and academic research.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. The container should be kept in a dry, well-ventilated area designated for research chemicals. Allow the product to reach room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	Yellow to orange powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.