Description

1-(2,6-Difluorophenyl)Cyclopropane-1-Carbonitrile is a high-value, multi-functional organic intermediate featuring a cyclopropane ring and a nitrile group on a difluorinated aromatic scaffold. This unique structure makes it a critical building block for the synthesis of advanced pharmaceutical compounds and agrochemicals, where its rigidity and electronic properties are highly desirable. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, leveraging the fluorine atoms for enhanced biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of monomers or additives for high-performance polymers with specific thermal or chemical resistance properties.
• Fluorine Chemistry Building Block: Utilized in exploratory chemistry to introduce the difluorophenyl-cyclopropane motif into more complex molecular architectures.

Basic Information

Product Name	1-(2,6-Difluorophenyl)Cyclopropane-1-Carbonitrile
CAS No.	124276-65-9
Molecular Formula	C10H7F2N
Molecular Weight	179.17 g/mol
Synonyms	1-(2,6-Difluorophenyl)cyclopropanecarbonitrile; Cyclopropanecarbonitrile, 1-(2,6-difluorophenyl)-; 2,6-Difluorophenylcyclopropanecarbonitrile; 1-(2,6-Difluorophenyl)cyclopropyl cyanide; (2,6-Difluorophenyl)cyclopropanecarbonitrile; 124276-65-9; 1-(2,6-Difluorophenyl)-1-cyclopropanecarbonitrile
EINECS	Contact for details

Quality Control

Our 1-(2,6-Difluorophenyl)Cyclopropane-1-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support custom synthesis and can tailor purity grades (e.g., >97%, >98%, >99%) to meet specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.