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7(O)-(6-Deoxy-2-o-Methyl-α-L-Talopyranosyl)Adriamycinone CAS NO 124209-63-8
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CAS No.:124209-63-8
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
7(O)-(6-Deoxy-2-o-Methyl-α-L-Talopyranosyl)Adriamycinone is a specialized anthracycline glycoside derivative, primarily recognized as a key intermediate in the synthesis of advanced pharmaceutical compounds. Its value lies in its structural role for developing novel chemotherapeutic agents and for biochemical research into drug mechanisms and resistance. This high-purity intermediate is essential for pharmaceutical R&D laboratories, biotechnology firms, and academic institutions focused on oncology drug discovery and development.
Application
- Pharmaceutical Intermediate: Critical building block for the synthesis of novel anthracycline-based chemotherapeutic agents and analogs.
- Oncology Research: Used in biochemical and pharmacological studies to investigate structure-activity relationships (SAR) and mechanisms of action of anticancer drugs.
- Drug Discovery & Development: Serves as a precursor in medicinal chemistry programs aimed at developing new anti-tumor compounds with improved efficacy or reduced side effects.
- Reference Standard: Employed as a high-purity analytical standard for quality control and method development in pharmaceutical manufacturing.
- Academic Research: Utilized in university and institutional labs for studies on drug metabolism, resistance pathways, and targeted drug delivery systems.
Basic Information
| Product Name | 7(O)-(6-Deoxy-2-o-Methyl-α-L-Talopyranosyl)Adriamycinone |
| CAS No. | 124209-63-8 |
| Molecular Formula | C31H35NO12 |
| Molecular Weight | 613.61 g/mol |
| Synonyms | 7-O-(6-Deoxy-2-O-methyl-α-L-talopyranosyl)adriamycinone; 7-O-(6-Deoxy-2-O-methyl-α-L-talopyranosyl)doxorubicinone; 2'-O-Methyl-α-L-talosyldoxorubicinone; ID-6105; (8S,10S)-10-[(3-Amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-8-glycoloyl-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-5,12-naphthacenedione 7-(6-deoxy-2-O-methyl-α-L-talopyranoside); Talosylated doxorubicinone intermediate. |
| EINECS | Contact for details |
Quality Control
Our 7(O)-(6-Deoxy-2-o-Methyl-α-L-Talopyranosyl)Adriamycinone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept in a desiccated environment to prevent moisture uptake. For long-term storage, consider storing under an inert atmosphere.
Specification
| Item | Specification |
|---|---|
| Appearance | Orange to red powder |
| Identification (HPLC) | Conforms to reference standard |
| Identification (IR) | Conforms to structure |
| Purity (HPLC) | ≥ 95.0% |
| Water Content (KF) | ≤ 5.0% |
| Residue on Ignition | ≤ 1.0% |
| Heavy Metals | ≤ 20 ppm |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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