Description

(8S-Cis)-8-Acetyl-10-((6-Deoxy-2-o-Methyl-α-L-Talopyranosyl)Oxy)-7,8,9,10-Tetrahydro-6,8,11-Trihydroxy-1-Methoxy-5,12-Naphthacenedione is a complex, high-purity anthracycline derivative with significant pharmaceutical research value. This compound is critical for advanced research and development in oncology and antibiotic discovery due to its intricate glycosylated structure. It is primarily sought by pharmaceutical R&D laboratories, academic research institutions, and fine chemical manufacturers engaged in the synthesis of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor or reference standard in the research and development of novel anthracycline-based chemotherapeutic agents.
• Oncology Research: Used in biochemical and pharmacological studies to investigate mechanisms of action, structure-activity relationships (SAR), and potential efficacy against various cancer cell lines.
• Antibiotic Development: Employed in the discovery and synthesis of new antibiotic compounds, leveraging the core anthracycline scaffold known for its antimicrobial properties.
• Academic & Institutional Research: Utilized in university and government laboratories for fundamental chemical and biological research, including enzyme inhibition studies and molecular modeling.
• Reference Standard: Acts as a high-purity analytical standard for quality control (QC) and method development in analytical laboratories, ensuring batch consistency in related API manufacturing.
• Process Chemistry: Applied in route scouting and optimization for the scalable synthesis of complex natural products and their analogues.

Basic Information

Product Name	(8S-Cis)-8-Acetyl-10-((6-Deoxy-2-o-Methyl-α-L-Talopyranosyl)Oxy)-7,8,9,10-Tetrahydro-6,8,11-Trihydroxy-1-Methoxy-5,12-Naphthacenedione
CAS No.	124209-61-6
Molecular Formula	C28H30O13
Molecular Weight	574.53 g/mol
Synonyms	8-Acetyl-10-((6-deoxy-2-O-methyl-α-L-talopyranosyl)oxy)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-5,12-naphthacenedione; (8S-cis)-8-Acetyl-10-[(6-deoxy-2-O-methyl-α-L-talopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-5,12-naphthacenedione; 2-O-Methyl-α-L-amicetosyl adriamycinone; 2'-O-Methyl-α-L-amicetosyl adriamycinone; A related analogue of Aclacinomycin; Anthracycline derivative 124209-61-6.
EINECS	Contact for details

Quality Control

Our (8S-Cis)-8-Acetyl-10-((6-Deoxy-2-o-Methyl-α-L-Talopyranosyl)Oxy)-7,8,9,10-Tetrahydro-6,8,11-Trihydroxy-1-Methoxy-5,12-Naphthacenedione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label. This product is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere). For long-term storage, consider storing under an inert gas such as argon or nitrogen in a sealed container to maintain stability.

Specification

Item	Specification
Appearance	Orange to red powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.