Description

Gentisone Hc is a high-purity pharmaceutical intermediate and active ingredient, identified by CAS NO 123902-40-9. It is a critical compound valued for its specific pharmacological activity and is essential in the development and manufacturing of advanced therapeutic formulations. This product is primarily required by pharmaceutical R&D laboratories and production facilities engaged in creating specialized dermatological and anti-inflammatory medications.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of topical corticosteroid medications.
• Active Pharmaceutical Ingredient (API): Used in the formulation of creams, ointments, and lotions for treating skin inflammation, eczema, and psoriasis.
• Veterinary Medicine: Employed in topical preparations for treating dermatological conditions in animals.
• Research & Development: Serves as a reference standard and a starting material for novel drug discovery programs targeting inflammatory pathways.
• Compounding Pharmacy: Used by specialized pharmacies to prepare customized topical formulations as per physician prescriptions.

Basic Information

Product Name	Gentisone Hc
CAS No.	123902-40-9
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Gentisone HC; Hydrocortisone Gentisate; Gentisic Acid Hydrocortisone Ester; 2-Hydroxy-5-[(1S,2R,3aS,3bS,9aS,9bR,10S,11aS)-1,2,9a,10-tetrahydroxy-9b-fluoro-1,6,8-trimethyl-1,2,3,3a,3b,4,5,7,8,9,9a,9b,10,11-tetradecahydro-11aH-cyclopenta[a]phenanthren-10-yl]oxycarbonyl]benzoic acid; Hydrocortisone 21-gentisate
EINECS	Contact for details

Quality Control

Our Gentisone Hc is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and impurity profiles as per agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.