Description

2-Fluoro-4-(4-Methoxyphenyl)Benzonitrile is a high-value fluorinated aromatic nitrile building block, essential for advanced organic synthesis. Its molecular structure, featuring both a fluorine atom and a benzonitrile group attached to a biphenyl core, makes it a critical intermediate for creating complex molecules with tailored electronic and steric properties. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly in kinase inhibitor and CNS-active compound research.
• Agrochemical Development: Used in the research and production of advanced herbicides and pesticides, where the fluorine atom enhances biological activity and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for synthesizing fluorinated liquid crystal molecules and electron-transport materials for organic light-emitting diodes (OLEDs).
• Organic Synthesis Reagent: A versatile intermediate for Suzuki-Miyaura and other cross-coupling reactions to construct complex biaryl systems.
• Chemical Research & Development: Used in academic and industrial R&D for exploring new reactions and creating libraries of fluorinated compounds for screening.

Basic Information

Product Name	2-Fluoro-4-(4-Methoxyphenyl)Benzonitrile
CAS No.	123864-93-7
Molecular Formula	C14H10FNO
Molecular Weight	227.24 g/mol
Synonyms	4'-Methoxy-2-fluorobiphenyl-4-carbonitrile; 2-Fluoro-4'-(methoxy)[1,1'-biphenyl]-4-carbonitrile; 2-Fluoro-4-(4-methoxyphenyl)benzonitrile; [1,1'-Biphenyl]-4-carbonitrile, 2-fluoro-4'-methoxy-; 4-(4-Methoxyphenyl)-2-fluorobenzonitrile
EINECS	Contact for details

Quality Control

Our 2-Fluoro-4-(4-Methoxyphenyl)Benzonitrile is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications. Our quality commitment supports applications in cGMP environments and advanced research.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥97.0% (Standard Grade)
Purity (HPLC, Area%)	≥98.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.