Description

2,6-Difluoro-4-Methoxybenzonitrile is a high-purity fluorinated aromatic nitrile building block of significant importance in advanced organic synthesis. Its value lies in its versatile reactivity, where the nitrile and methoxy groups serve as handles for further functionalization, while the fluorine atoms impart desirable electronic and metabolic properties to target molecules. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, where the fluorine atoms enhance biological activity and environmental stability.
• Liquid Crystal Materials: Serves as a precursor in the manufacture of fluorinated liquid crystals for high-performance displays.
• Organic Electronics: Employed in the development of novel organic semiconductors and electron-transport materials.
• Chemical Research: A valuable building block for academic and industrial research in fluorination chemistry and heterocyclic compound synthesis.
• Advanced Polymer Modification: Used to introduce fluorine and cyano functionalities into polymer backbones to alter thermal and solubility properties.

Basic Information

Product Name	2,6-Difluoro-4-Methoxybenzonitrile
CAS No.	123843-66-3
Molecular Formula	C8H5F2NO
Molecular Weight	169.13 g/mol
Synonyms	4-Methoxy-2,6-difluorobenzonitrile; 2,6-Difluoro-4-methoxybenzenecarbonitrile; 2,6-Difluoro-p-anisonitrile; Benzonitrile, 2,6-difluoro-4-methoxy-; 2,6-Difluoro-4-methoxy-benzonitrile; 2,6-Difluoro-4-methoxy-phenyl cyanide
EINECS	Contact for details

Quality Control

Our 2,6-Difluoro-4-Methoxybenzonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.