Description

4-Fluoro-1-Nitro-2-(Trifluoromethoxy)Benzene is a high-value fluorinated aromatic building block, essential for synthesizing advanced chemical intermediates. Its unique structure, featuring both nitro and trifluoromethoxy substituents, makes it a critical precursor in the development of active pharmaceutical ingredients (APIs) and agrochemicals. This compound is primarily sought after by R&D laboratories and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for creating novel compounds with enhanced biological activity and physical properties.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-infective therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, where the fluorine and trifluoromethoxy groups contribute to efficacy and environmental stability.
• Liquid Crystal Materials: Serves as a precursor in the manufacture of fluorinated liquid crystals for display technologies.
• Organic Electronics: Employed in the development of materials for organic light-emitting diodes (OLEDs) and semiconductors.
• Dye and Pigment Intermediate: Utilized in the synthesis of specialized, high-performance colorants.
• Cross-Coupling Reactions: Acts as a substrate in Suzuki, Buchwald-Hartwig, and other palladium-catalyzed coupling reactions to create complex biaryl structures.

Basic Information

Product Name	4-Fluoro-1-Nitro-2-(Trifluoromethoxy)Benzene
CAS No.	123572-65-6
Molecular Formula	C7H3F4NO3
Molecular Weight	225.10 g/mol
Synonyms	1-Fluoro-4-nitro-2-(trifluoromethoxy)benzene; 2-Trifluoromethoxy-4-fluoronitrobenzene; 4-Fluoro-2-(trifluoromethoxy)nitrobenzene; 4-Fluoro-1-nitro-2-(trifluoromethoxy)benzene; 4-Fluoro-2-(trifluoromethoxy)-1-nitrobenzene; Benzene, 1-fluoro-4-nitro-2-(trifluoromethoxy)-; 4-Fluoro-α,α,α-trifluoro-2-nitroanisole
EINECS	Contact for details

Quality Control

Our 4-Fluoro-1-Nitro-2-(Trifluoromethoxy)Benzene is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments. Our quality commitment aligns with cGMP and ISO standards to meet the stringent requirements of our global pharmaceutical and agrochemical partners.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere for prolonged storage to prevent degradation.

Specification

Item	Specification
Appearance	White to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.