Description

Seldane-D CAS NO 123245-78-3 is a high-purity chemical compound, also known as terfenadine, primarily recognized for its antihistaminic properties. This active pharmaceutical ingredient (API) is critical for ensuring the efficacy and safety of pharmaceutical formulations targeting allergic conditions. It is essential for manufacturers in the pharmaceutical and research and development sectors who require a reliable and consistent raw material for drug synthesis and advanced studies.

Application

• Pharmaceutical API: Primary use as the active ingredient in antihistamine medications for treating seasonal allergies and allergic rhinitis.
• Reference Standard: Serves as a certified reference material for quality control and analytical method validation in pharmaceutical laboratories.
• Research Chemical: Used in biochemical and pharmacological research to study histamine H1-receptor antagonism and related pathways.
• Formulation Development: A key component in the development and stability testing of solid oral dosage forms such as tablets and capsules.
• Generic Drug Manufacturing: Essential for the production of generic terfenadine-based pharmaceutical products.
• Metabolite Studies: Utilized in studies investigating the metabolism and pharmacokinetics of antihistamine drugs.

Basic Information

Product Name	Seldane-D
CAS No.	123245-78-3
Molecular Formula	C32H41NO2
Molecular Weight	471.68 g/mol
Synonyms	Terfenadine; (±)-Terfenadine; α-[4-(1,1-Dimethylethyl)phenyl]-4-(hydroxydiphenylmethyl)-1-piperidinebutanol; 1-(4-tert-Butylphenyl)-4-[4-(α-hydroxy-α-phenylbenzyl)piperidino]butan-1-ol; Seldane; Triludan; Teldane; Teldanex
EINECS	Contact for details

Quality Control

Our Seldane-D is manufactured under strict quality management systems to meet the rigorous demands of the pharmaceutical industry. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR, ensuring compliance with in-house specifications aligned with major pharmacopoeial standards. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed to protect the product from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.0% Any single impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.