Description

Emedastinen-Oxide CAS NO 122484-65-5 is a specific chemical intermediate of significant importance in advanced pharmaceutical synthesis. This compound serves as a critical precursor in the development and manufacturing of active pharmaceutical ingredients (APIs), particularly in the antihistamine therapeutic class. It is essential for research institutions, pharmaceutical development laboratories, and large-scale API manufacturers seeking reliable, high-purity building blocks for complex synthetic pathways.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the production of Emedastine and related antihistamine APIs.
• Active Pharmaceutical Ingredient (API) Synthesis: Used in multi-step organic synthesis for constructing complex molecular frameworks in drug manufacturing.
• Research & Development (R&D): Employed in medicinal chemistry for the discovery and optimization of new therapeutic agents targeting histamine receptors.
• Process Chemistry: Utilized in scaling up synthetic routes from laboratory to pilot plant and commercial production scales.
• Reference Standard: Serves as a certified reference material (CRM) for analytical method development and quality control in pharmaceutical analysis.
• Chemical Synthesis: Acts as a versatile building block for creating novel chemical entities in specialized organic chemistry applications.

Basic Information

Product Name	Emedastinen-Oxide
CAS No.	122484-65-5
Molecular Formula	C17H26N2O2
Molecular Weight	290.41 g/mol
Synonyms	Emedastine N-Oxide; 1-(2-Ethoxyethyl)-2-(hexahydro-4-methyl-1H-1,4-diazepin-1-yl)-1H-benzimidazole N-Oxide; Emedastine Oxide; Emedastine Impurity C; Emedastine Related Compound C; 1-(2-Ethoxyethyl)-2-[(4-methyl-1,4-diazepan-1-yl)]-1H-benzimidazole 3-Oxide
EINECS	Contact for details

Quality Control

Our Emedastinen-Oxide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR spectroscopy, and stringent control of residual solvents and related substances. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, ensuring compliance with cGMP and relevant pharmacopeial guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.