Description

4-(Cyanomethyl)-2,3,5,6-tetrafluorobenzonitrile is a specialized fluorinated aromatic nitrile compound that serves as a critical building block in advanced chemical synthesis. Its unique structure, featuring both a cyano and a cyanomethyl group on a perfluorinated benzene ring, makes it a valuable precursor for creating complex molecules with tailored electronic and physical properties. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors, where it is used to develop novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key synthon for the development of fluorinated drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, where the fluorine atoms enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a core building block for fluorinated liquid crystals and organic light-emitting diode (OLED) materials, improving device performance.
• Polymer & Resin Modifier: Incorporated into specialty polymers to impart enhanced chemical resistance, thermal stability, and low surface energy properties.
• Organic Synthesis Reagent: A versatile reagent in cross-coupling reactions and cyano-chemistry for constructing complex aromatic systems in R&D laboratories.
• Electronic Chemicals: Potential use in the synthesis of dielectric materials and etchants for the semiconductor manufacturing process.

Basic Information

Product Name	4-(Cyanomethyl)-2,3,5,6-Tetrafluorobenzonitrile
CAS No.	121623-97-0
Molecular Formula	C9H2F4N2
Molecular Weight	214.12 g/mol
Synonyms	2,3,5,6-Tetrafluoro-4-(cyanomethyl)benzonitrile; 1,2,4,5-Tetrafluoro-3,6-bis(cyanomethyl)benzene; 4-(Cyanomethyl)tetrafluorophthalonitrile; Tetrafluorobenzonitrile, 4-(cyanomethyl)-; 2,3,5,6-Tetrafluoro-1,4-phenylenediacetonitrile; TFPN; Contact for additional trade names and abbreviations.
EINECS	Contact for details

Quality Control

Our production of 4-(Cyanomethyl)-2,3,5,6-tetrafluorobenzonitrile adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including HPLC, GC, NMR, and IR spectroscopy. We provide comprehensive Certificates of Analysis (COA) detailing purity, identity, and impurity profiles. Our quality system is designed to support cGMP and ISO standards for customers in regulated industries, ensuring reliable supply for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.