Description

3-Acetylmethyl-1,2-Difluoro-4-Nitrobenzene is a specialized fluorinated and nitrated aromatic compound, serving as a high-value synthetic intermediate. Its unique structure, featuring both electron-withdrawing nitro and acetyl groups alongside fluorine atoms, makes it a critical building block for constructing complex molecules. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and advanced materials sectors for applications in medicinal chemistry and agrochemical synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Research: Used in the development of next-generation herbicides and pesticides, where the fluorine atoms enhance biological activity and environmental stability.
• Liquid Crystal & OLED Material Synthesis: Serves as a building block for fluorinated organic electronic materials, contributing to improved performance in display and lighting technologies.
• Dye & Pigment Chemistry: Employed in the synthesis of specialized fluorinated dyes and pigments that offer superior lightfastness and color properties.
• Cross-Coupling Reactions: Acts as a substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille) to create complex biaryl structures common in many functional materials.
• Academic & Contract Research: Utilized in university and CRO (Contract Research Organization) laboratories for methodological studies and the exploration of new chemical spaces.

Basic Information

Product Name	3-Acetylmethyl-1,2-Difluoro-4-Nitrobenzene
CAS No.	121247-16-3
Molecular Formula	C9H7F2NO3
Molecular Weight	215.15 g/mol
Synonyms	1-(2,3-Difluoro-4-nitrophenyl)ethanone; 2',3'-Difluoro-4'-nitroacetophenone; 2,3-Difluoro-4-nitroacetophenone; 3-Acetyl-1,2-difluoro-4-nitrobenzene; 3-Acetylmethyl-1,2-difluoro-4-nitrobenzene; 3-Acetyl-1,2-difluoronitrobenzene; 3-Acetyl-1,2-difluoro-4-nitrobenzene; 3-Acetylmethyl-1,2-difluoro-4-nitrobenzene
EINECS	Contact for details

Quality Control

Our 3-Acetylmethyl-1,2-Difluoro-4-Nitrobenzene is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the exacting standards required for research and process chemistry. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in light-resistant secondary packaging.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.