Description

Tetrabutylphosphonium Fluoride is a versatile and highly reactive organophosphonium salt, primarily valued for its dual role as a potent fluoride ion source and a strong, non-nucleophilic base. This compound is critical for driving advanced organic synthesis, particularly in applications where traditional bases are ineffective or where anhydrous fluoride is required. It is an essential reagent for research and development chemists, process engineers, and manufacturers in the pharmaceutical, agrochemical, and specialty materials sectors seeking to perform demanding transformations with high efficiency.

Application

• Nucleophilic Fluorination Reactions: A key reagent for introducing fluorine atoms into organic molecules, crucial for developing pharmaceuticals and agrochemicals with enhanced metabolic stability and bioavailability.
• Promoter for Silylation and Desilylation: Acts as an efficient catalyst or activator in protecting group chemistry, facilitating the introduction or removal of silyl groups in complex multi-step syntheses.
• Phase-Transfer Catalyst (PTC): Used to accelerate reactions between reagents in immiscible phases, improving yield and selectivity in industrial-scale processes.
• Strong Non-Nucleophilic Base: Employed in base-sensitive reactions, such as deprotonations and eliminations, where its bulky structure minimizes unwanted side reactions.
• Polymerization Catalyst: Utilized in the synthesis of specialized polymers and resins, where it can initiate or control specific polymerization mechanisms.
• Electrolyte Additive: Investigated for use in advanced battery systems to improve ionic conductivity and electrode stability.

Basic Information

Item	Detail
Product Name	Tetrabutylphosphonium Fluoride
CAS No.	121240-56-0
Molecular Formula	C₁₆H₃₆FP
Molecular Weight	278.43 g/mol
Synonyms	Tetra-n-butylphosphonium Fluoride; TBPF; Phosphonium, tetrabutyl-, fluoride; Tetrabutylphosphonium fluoride solution; Fluorotetrabutylphosphorane; TBAP-F
EINECS	Contact for details

Quality Control

Our Tetrabutylphosphonium Fluoride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including assay (by titration), identification (IR), and impurity profiling, to ensure it meets the high-purity standards required for sensitive synthetic applications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under a dry inert atmosphere to maintain purity and reactivity. Keep away from incompatible materials such as strong acids.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (Tetrabutylphosphonium Fluoride)	≥ 98.0 %
Water Content (KF)	≤ 1.0 %
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.