Description

Adaprolol is a selective β-adrenergic receptor antagonist, a key pharmaceutical intermediate in the synthesis of advanced cardiovascular agents. Its precise molecular structure and high purity are critical for ensuring the efficacy and safety of the final active pharmaceutical ingredient (API). This compound is essential for research institutions and pharmaceutical manufacturers focused on developing and producing novel β-blocker medications. Global supply chain reliability and stringent quality control are paramount for its successful application.

Application

• Primary intermediate in the synthesis of advanced β-blocker (β-blocker) APIs for cardiovascular therapies.
• Key building block for pharmaceutical research and development targeting hypertension and angina.
• Used in process chemistry and scale-up studies for new drug candidates.
• Reference standard for analytical method development and quality control in pharmaceutical laboratories.
• Critical material for GMP-compliant manufacturing of finished dosage forms.

Basic Information

Product Name	Adaprolol
CAS No.	121009-31-2
Molecular Formula	C16H25N3O3
Molecular Weight	307.39 g/mol
Synonyms	1-(tert-Butylamino)-3-[(5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophen-4-ylidene)amino]-2-propanol; Adaprololum; B-24/76; Adaprolol [INN]; Adaprolol (INN); Adaprolol (B-24/76); UNII-3Q6Q8M516W
EINECS	Contact for details

Quality Control

Our Adaprolol is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We support compliance with ICH guidelines and can tailor specifications to meet specific pharmacopeial standards (e.g., USP, EP) or custom requirements for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.0% Any single impurity ≤ 0.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.