Description

Butixocort CAS NO 120815-74-9 is a synthetic corticosteroid derivative, specifically a 17α-butyrate ester of a halogenated prednisolone analog. This compound is valued for its potent topical anti-inflammatory and immunosuppressive activity with a favorable therapeutic index, minimizing systemic side effects. It is primarily required by pharmaceutical R&D and manufacturing sectors for the development and production of advanced topical dermatological formulations, such as creams and ointments, targeting inflammatory skin conditions.

Application

• Topical Corticosteroid Formulations: Key active pharmaceutical ingredient (API) in prescription-strength creams, ointments, and lotions for treating severe eczema, psoriasis, and dermatitis.
• Dermatological R&D: Used in preclinical and clinical research to develop new topical therapies with enhanced potency and reduced skin atrophy potential.
• Veterinary Medicine: Incorporated into topical preparations for managing inflammatory skin disorders in animals.
• Compound Synthesis: Serves as a critical intermediate or reference standard in the organic synthesis of novel steroid-based pharmaceuticals.

Basic Information

Product Name	Butixocort
CAS No.	120815-74-9
Molecular Formula	C26H33FO6
Molecular Weight	460.54 g/mol
Synonyms	Butixocort; Butixocort 17α-butyrate; 9α-Fluoro-11β,21-dihydroxy-16α,17α-isopropylidenedioxy-1,4-pregnadiene-3,20-dione 17α-butyrate; 9α-Fluoro-11β,21-dihydroxy-16α,17α-(isopropylidenedioxy)pregna-1,4-diene-3,20-dione 17α-butyrate; Halogenated corticosteroid ester; Prednisolone derivative butyrate
EINECS	Contact for details

Quality Control

Our Butixocort is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency, meeting high-grade pharmaceutical standards. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with specifications for Assay, Related Substances, Residual Solvents, and Identification.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccated environment after opening to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.